The optimal management, including the role of chemotherapy in the treatment of WDPM, remains unsettled. The authors describe two cases of WDPM in women of the same family siblings ; the elder with WDPM of the pleura and peritoneum with a year survival period and the younger with a WDPM of the peritoneum diagnosed in and uveal melanoma diagnosed in Neither patient had any known exposure to asbestos fibers or any other mineral carcinogens. After the concurrent diagnosis of WDPM and uveal melanoma, genetic diagnosis was carried out taking into consideration that these two malignancies were recently associated with hereditary BAP1 gene mutations and it was positive for both the patients.
This article provides evidence of the wide clinical spectrum of cancer susceptibility associated with a BAP1 germline mutation. In vitro activity of silicon carbide whiskers in comparison to other industrial fibers using four cell culture systems. Silicon carbide whiskers SiCW and continuous glass filaments are important components of composite materials having potentially widespread use in the automotive, aerospace, and power generation industries.
We determined the in vitro We determined the in vitro activity of three well-characterized samples of silicon carbide whiskers and a continuous glass filament sample in four different cellular assays and compared this to the activities of UICC crocidolite, JM Code glass microfiber, and erionite in the same assay systems. The SiCW had a diameter range of 0.
The SiCW was significantly toxic; on a mass basis, one SiCW sample was more toxic than crocidolite; however, JM Code glass microfiber, which is not toxic in vivo i. The glass filament sample was the least cytotoxic of all the samples tested. On a fiber number basis, all three SiCW samples were more toxic than crocidolite.
The results of our study showed that SiCW exhibits significant in vitro biological reactivity. Thus, despite the caution that must be exercised in extrpolating the results of in vitro studies to conclusions about in vivo health effects, SiCW should be considered toxic until further toxicological data are available. Thermal behaviour of actinolite asbestos. Actinolite is one of the six minerals belonging to the group of asbestos minerals.
There is increasing concern regarding the potential health risks from exposure to naturally occurring asbestos and asbestos-containing materials. The correct distinction of the fibrous asbestos minerals is very important not only from a scientific point of view, but also from a legislative perspective.
Asbestos actinolite is currently the only asbestos mineral that has not been fully characterized from the thermal point of view. In order to compensate for this gap in scientific literature, this paper discusses the thermal behaviour of actinolite asbestos using thermogravimetric and differential scanning calorimetry. The thermal decomposition process of actinolite asbestos consists of two distinct events followed by recrystallization into new stable crystalline phases which preserved the original fibrous morphology known as pseudomorphosis.
The thermal analysis may prove to be useful for actinolite identification and discrimination, particularly in the case of natural massive samples where asbestos tremolite— actinolite amphiboles are mutually intermixed. Furthermore, profound knowledge of the thermal behaviour of this asbestos mineral may provide us with the relevant data for understanding the crystal—chemical transformations of asbestos through thermal inertization treatment. Survival patterns for malignant mesothelioma: The seer experience. Malignant mesothelioma: attributable risk of asbestos exposure.
To evaluate a case-control study of malignant mesothelioma through patterns of exposure to asbestos based upon information from telephone interviews with next of kin. Potential cases, identified from medical files and death certificates, Potential cases, identified from medical files and death certificates, included all people diagnosed with malignant mesothelioma and registered during by the Los Angeles County Cancer Surveillance Program, the New York State Cancer Registry excluding New York City , and 39 large Veterans Administration hospitals.
Direct exposure to asbestos was determined from responses to three types of questions: specific queries as to any exposure to asbestos; occupational or non-vocational participation in any of nine specific activities thought to entail exposure to asbestos While many public health threats are now widely appreciated by the public, the risks from asbestos exposure remain poorly understood, even in high-risk groups. This article makes the case that asbestos exposure is an important, ongoing This article makes the case that asbestos exposure is an important, ongoing global health threat, and argues for greater policy efforts to raise awareness of this threat.
It also proposes the extension of asbestos bans to developing countries and increased public subsidies for asbestos testing and abatement.
Asbestos Research | The Australian Asbestos Network
For a few years now in Italy there has been wide discussion on the advisability of developing health surveillance programmes for workers who were exposed to occupational carcinogens in the past incompliance with Italian D. The purpose of the present paper was to contribute to the discussion on operative guidelines for public or private Occupational Health Services intending to address this issue.
A cross-sectional survey was undertaken on former workers of a glass factory located in Leghorn, Italy. A structured questionnaire was developed in order to standardize the collection of occupational and health histories. ISBN: To evaluate the contribution of reactive nitrogen species to inflammation by asbestos, Fischer rats were exposed to crocidolite or chrysotile asbestos by inhalation to determine whether increases occurred in nitric oxide NO.
Asbestos: mining exposure, health effects and policy implications
Temporal patterns of NO. Studies suggest that NO. Gefahrstoffe in Museumsobjekten — Erhaltung oder Entsorgung? Stark betroffen sind unter anderem historische Chemikalien- und Medikamentensammlungen oder technische Objekte mit Asbest- und Quecksilberbestandteilen. Substances which pose a potential chemical hazard normally occur either in a pure form or as a component in a mixture in the collections of many museum institutions. Due to their characteristics — combustibility, inflammability, toxicity, danger to health or the environment — they need to be managed apart.
The most affected are historic collections of chemicals and medication, and technical objects containing asbestos and mercury.
In addition to these hazards there is a considerable amount of organic materials that have been contaminated with biocides as pest control in the past. Even though the management of radioactive substances actually falls under the regulations for radiation protection rather than those for hazardous substances, such substances also demand special treatment and handling in regard to storage, exhibition and conservation.
In view of the restrictive laws governing such substances, the safe and respectful management of affected collection objects poses a new and complex challenge for museums. The development of strategies for the management of hazardous substances is urgent. Strategic approaches have to take not only legislation but also conservation guidelines into account. Here in particular the valid tennet is that only a thorough knowledge of the object leads to its intelligent management. In the following paper an overview of the hazardous objects will be presented and the conflict between preservation and disposal more closely examined.
Der Einsatz von Asbest war aufgrund der Deren technische Anforderungen bestimmten die Art des Asbestproduktes. Wetzenkircher, V. It gives an overview of the asbestos Related Topics. Follow Following. Shipyard Technology. Academic Capitalism. Spatial History. The Great Depression of s. Product liability. Although chest x-rays cannot detect asbestos fibers in the lungs, they can help identify any early signs of lung disease resulting from asbestos exposure 2.
A lung biopsy, which detects microscopic asbestos fibers in pieces of lung tissue removed by surgery , is the most reliable test to confirm exposure to asbestos 2. A bronchoscopy is a less invasive test than a biopsy and detects asbestos fibers in material that is rinsed out of the lungs 2.
Asbestos data collections
It is important to note that these procedures cannot determine how much asbestos an individual may have been exposed to or whether disease will develop. Department of Labor DOL and is the Federal agency responsible for health and safety regulations in maritime, construction, manufacturing, and service workplaces. OSHA established regulations dealing with asbestos exposure on the job, specifically in construction work, shipyards, and general industry, that employers are required to follow.
Workers should use all protective equipment provided by their employers and follow recommended workplace practices and safety procedures. Workers who are concerned about asbestos exposure in the workplace should discuss the situation with other employees, their employee health and safety representative, and their employers. If necessary, OSHA can provide more information or make an inspection. Mine workers can contact MSHA at:. NIOSH conducts asbestos-related research, evaluates work sites for possible health hazards, and makes exposure control recommendations. In addition, NIOSH distributes publications on the health effects of asbestos exposure and can suggest additional sources of information.
NIOSH can be contacted at:. Some people with asbestos-related illness may be eligible for Medicare coverage. Department of Labor DOL website. Benefits include wage replacement, payment for medical care, and, where necessary, medical and vocational rehabilitation assistance in returning to work.
Information about eligibility and how to file a claim for benefits under either of these programs is available from:. Veterans can receive treatment for service-connected and nonservice-connected medical conditions. This agency works in close collaboration with local, state, and other Federal agencies, with tribal governments, and with communities and local health care providers to help prevent or reduce harmful human health effects from exposure to hazardous substances.
The ATSDR provides information about asbestos and where to find occupational and environmental health clinics. The U.
The Asbestos Ombudsman focuses on asbestos in schools and handles questions and complaints. Both the TSCA Hotline and the Asbestos Ombudsman can provide publications on a number of topics, particularly on controlling asbestos exposure in schools and other buildings. The Ombudsman operates a toll-free hotline for small businesses, trade associations, and others seeking free, confidential help. Questions may be directed to:.
Released in April , this brochure includes work practices for both automotive professionals and home mechanics that may be used to avoid asbestos exposure. It also summarizes existing OSHA regulatory requirements for professional auto mechanics. The CPSC maintains a toll-free hour hotline where callers can obtain product safety and other agency information and report unsafe products. In addition, CPSC publications provide guidelines for repairing and removing asbestos, and general information about asbestos in the home.
CPSC can be contacted at:. Office of Information and Public Affairs U. Individuals can also contact their local or state health department with questions or concerns about asbestos. Menu Contact Dictionary Search. Understanding Cancer. What Is Cancer? Cancer Statistics. Cancer Disparities. Cancer Causes and Prevention.
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